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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 230 - 242 (13page)
- DOI
- https://doi.org/10.1186/s40824-021-00224-8
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초록· 키워드
오류제보하기
Exosomes are nano-sized cargos with a lipid bilayer structure carrying diverse biomolecules including lipids, proteins, and nucleic acids. These small vesicles are secreted by most types of cells to communicate with each other. Since exosomes circulate through bodily fluids, they can transfer information not only to local cells but also to remote cells. Therefore, exosomes are considered potential biomarkers for various treatments. Recently, studies have shown the efficacy of exosomes in skin defects such as aging, atopic dermatitis, and wounds. Also, exosomes are being studied to be used as ingredients in commercialized skin treatment products. In this review, we discussed the need for exosomes in skin therapy together with the current challenges. Moreover, the functional roles of exosomes in terms of skin treatment and regeneration are overviewed. Finally, we highlighted the major limitations and the future perspective in exosome engineering.
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참고문헌 (133)
참고문헌 신청
Wei X / 2013 / Mesenchymal stem cells : a new trend for cell therapy / Acta Pharmacol Sin 34(6):747~754
Orciani M / 2013 / Skin-derived mesenchymal stem cells: isolation, culture, and characterization / Springer :275~283
Pelekanos RA / 2016 / Isolation and expansion of mesenchymal stem/stromal cells derived from human placenta tissue / J Vis Exp 112:e54204
Amati E / 2017 / Generation of mesenchymal stromal cells from cord blood : evaluation of in vitro quality parameters prior to clinical use / Stem Cell Res Ther 8(1):1~15
Nagamura-Inoue T / 2014 / Umbilical cord-derived mesenchymal stem cells : their advantages and potential clinical utility / World J Stem Cells 6(2):195~202
Orciani M / 2013 / Skin-derived mesenchymal stem cells: isolation, culture, and characterization / Springer :275~283
Pelekanos RA / 2016 / Isolation and expansion of mesenchymal stem/stromal cells derived from human placenta tissue / J Vis Exp 112:e54204
Amati E / 2017 / Generation of mesenchymal stromal cells from cord blood : evaluation of in vitro quality parameters prior to clinical use / Stem Cell Res Ther 8(1):1~15
Nagamura-Inoue T / 2014 / Umbilical cord-derived mesenchymal stem cells : their advantages and potential clinical utility / World J Stem Cells 6(2):195~202
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