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자료유형
학술저널
저자정보
Yue Zhuo (School of Acupuncture-moxibustion Tuina and Rehabilitation Hunan University of Chinese Medicine) Kun Ai (School of Acupuncture-moxibustion Tuina and Rehabilitation Hunan University of Chinese Medicine) Ke He (The Second Hospital of Hunan University of Chinese Medicine) Boyu Wu (The Second Hospital of Hunan University of Chinese Medicine) Jiaying Peng (School of Acupuncture-moxibustion Tuina and Rehabilitation Hunan University of Chinese Medicine) Jing Xiang (School of Acupuncture-moxibustion Tuina and Rehabilitation Hunan University of Chinese Medicine) Guanlin Zhang (School of Acupuncture-moxibustion Tuina and Rehabilitation Hunan University of Chinese Medicine) Ziyuan Jiao (School of Acupuncture-moxibustion Tuina and Rehabilitation Hunan University of Chinese Medicine) Ruixuan Zhou (School of Acupuncture-moxibustion Tuina and Rehabilitation Hunan University of Chinese Medicine) Hong Zhang (School of Acupuncture-moxibustion Tuina and Rehabilitation Hunan University of Chinese Medicine)
저널정보
대한척추신경외과학회 Neurospine Neurospine 제20권 제2호
발행연도
2023.6
수록면
507 - 524 (18page)
DOI
10.14245/ns.2244988.494

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Objective: Exosomes in the central nervous system (CNS) have become an attractive area of research with great value. However, few bibliometric analysis has been conducted. The study aimed to visualize the scientific trends and research hotspots of exosomes in the CNS by bibliometric analysis. Methods: All potential articles and reviews on exosomes in the CNS published in English from 2001 to 2021 were extracted from the Web of Science Core Collection. The visualiza tion knowledge maps of critical indicators, including countries/regions, institutions, au thors, journals, references, and keywords, were generated by CiteSpace and VOSviewer software. Besides, each domain's quantitative and qualitative analysis was also considered. Results: A total of 2,629 papers were included. The number of exosomes-related publica tions and citations regarding CNS increased yearly. These publications came from 2,813 in stitutions in 77 countries/regions, led by the United States and China. Harvard University was the most influential institution, while the National Institutes of Health was the most critical funding source. We identified 14,468 authors, among which Kapogiannis D had the most significant number of articles and the highest H-index, while Théry C was the most frequently co-cited. The cluster analysis of keywords generated 13 clusters. In summary, the topic of biogenesis, biomarker, and drug delivery will serve as hotspots in future research. Conclusion: Exosomes-related CNS research has gained considerable attention in the past 20 years. The sources and biological functions of exosomes and their promising role in diagnos ing and treating CNS diseases are considered hotspots in this field. The clinical translation of the results from exosomes-related CNS research will be of great importance in the future.

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