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논문 기본 정보

자료유형
학술저널
저자정보
Shuanglong Zhou (Zunyi Medical University) Jialing Huang (Zunyi Medical University) Yi Zhang (Zunyi Medical University) Hongsong Yu (Zunyi Medical University) Xin Wang (Zunyi Medical University)
저널정보
대한면역학회 Immune Network Immune Network Vol.24 No.2
발행연도
2024.4
수록면
4 - 20 (17page)

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초록· 키워드

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Exosomes are double phospholipid membrane vesicles that are synthesized and secreted by a variety of cells, including T cells, B cells, dendritic cells, immune cells, are extracellular vesicles. Recent studies have revealed that exosomes can play a significant role in under both physiological and pathological conditions. They have been implicated in regulation of inflammatory responses, immune response, angiogenesis, tissue repair, and antioxidant activities, particularly in modulating immunity in autoimmune diseases (AIDs). Moreover, variations in the expression of exosome-related substances, such as miRNA and proteins, may not only offer valuable perspectives for the early warning, and prognostic assessment of various AIDs, but may also serve as novel markers for disease diagnosis. This article examines the impact of exosomes on the development of AIDs and explores their potential for therapeutic application.

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ABSTRACT
INTRODUCTION
EXOs AND SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
EXOs AND RHEUMATOID ARTHRITIS (RA)
EXOs AND AUTOIMMUNE THYROID DISEASES (AITDs)
EXOs AND SJOGREN’S SYNDROME (SS)
EXOs AND MYASTHENIA GRAVIS (MG)
EXOs AND TYPE 1 DIABETES (T1DM)
EXOs AND MULTIPLE SCLEROSIS (MS)
APPLICATION PROSPECT OF EXOs TREATMENT
SUMMARY AND PROSPECT
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