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논문 기본 정보

자료유형
학술저널
저자정보
Atiporn Therdyothin (Dept.of Orthopaedics Faculty of Medicine Ramathibodi Hospital) Nacharin Phiphopthatsanee (South London and Maudsley NHS Foundation Trust United Kingdom) Wiwat Wajanavisit (Dept.of Orthopaedics Faculty of Medicine Ramathibodi Hospital) Patarawan Woratanarat (Dept.of Orthopaedics Faculty of Medicine Ramathibodi Hospital) Sukij Laohajaroensombat (Dept.of Orthopaedics Faculty of Medicine Ramathibodi Hospital) Tulyapruek Tawonsawatruk (Dept.of Orthopaedics Faculty of Medicine Ramathibodi Hospital)
저널정보
대한골다공증학회 Osteoporosis and Sarcopenia Osteoporosis and Sarcopenia Vol.6 No.3
발행연도
2020.1
수록면
151 - 159 (9page)

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Objectives: Ankle fractures are common in the elderly. However, their association with osteoporosis remains controversial. This systematic review aims to determine the relationship between ankle fracture and bone mineral density (BMD), and to investigate the risk of subsequent fractures after ankle fracture. Methods: MEDLINE and Scopus publications were searched from inception to March and April 2019, respectively. Articles were selected by 2 independent reviewers for cross-sectional, cohort, or casecontrol studies comparing BMD or subsequent fracture risk in low-energy ankle fractures patients with that of the normal population. Data extraction was performed by 2 investigators. Discrepancies were resolved with the third reviewer. Quality assessment was conducted using the modified NewcastleOttawa Scale. Results: Overall, 19 articles were included. The quality assessment showed a generally low-to-moderate risk of bias among studies, mainly due to potential confounders and inadequate follow-up. Of 13 studies exploring BMD in ankle fractured-patients, lower central and peripheral BMD was found in 3 and 2 studies, respectively. The risk of subsequent fracture was examined in 11 studies with relative risks ranging from 0.7 to 4.59. An increased risk of any subsequent fractures in women, both genders, and men was found in 5, 2, and 1 articles, respectively. Conclusions: Despite the lack of clear association with BMD, the contribution of ankle fracture to increased subsequent fracture risk and its associated microarchitectural changes cannot be overlooked. Moreover, its potential role as an early predictor of future fracture may promote secondary prevention. Further studies with longer follow-up and stricter confounder control are recommended.
#Osteoporosis #Ankle fracture #Bone mineral density #Fracture prediction #Risk factor

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참고문헌 (40)

참고문헌 신청
Pouresmaeili F / 2018 / A comprehensive overview on osteoporosis and its risk factors / Therapeut Clin Risk Manag 14:2029~2049 google schola Qaseem A / 2017 / Treatment of low bone density or osteoporosis to prevent fractures in men and women : a clinical practice guideline update from the American college of physicians / Ann Intern Med 166:818~839 google schola Johnson NA / 2017 / Risk of hip fracture following a wrist fracture-A meta-analysis / Injury 48:399~405 google schola Balasubramanian A / 2019 / Risk of subsequent fracture after prior fracture among older women / Osteoporos Int 30:79~92 google schola Ettinger B / 2003 / Limb fractures in elderly men as indicators of subsequent fracture risk / Arch Intern Med 163:2741~2747 google schola

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